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Is my Nexplanon implant the cause of my hives? #103/13

I've been waking up with what looks like bites or hives, usually just 1-5 at a time.  I'm praying its not bedbugs (which is very suspicious), but I've also heard the Nexplanon implant can cause hives.  It does tend to be worse in the morning? Anywhere I can get good information on this?

A:        Good morning, but it sounds as tho your mornings of late have not been so good.

Where are the bites or hives?  Do they recur at the same location usually?


Apparently allergic reactions can occur and women known to be allergic to etonogestrel should not use this contraceptive. 


See side-effects listed below, especially the very first one. 

Nexplanon (etonorgestrel (implant)) side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face , lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

  • Warmth, redness, swelling or oozing where the implant was inserted
  • Sudden numbness or weakness, especially on one side of the body
  • Severe pain or cramping in your pelvic area (may be only on one side)
  • Sudden severe headache, confusion, pain behind the eyes, problems with vision, speech or balance
  • Sudden cough, wheezing, rapid breathing, coughing up blood
  • Pain, swelling, warmth, or redness in one or both legs
  • Chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, general ill feeling
  • A breast lump
  • Swelling in your hands, ankles or feet
  • Jaundice (yellowing of the skin or eyes)
  • Symptoms of depression (sleep problems, weakness, tired feeling, mood changes) or dangerously high blood pressure (severe headache, blurred vision, buzzing in your ears, anxiety, confusion, chest pain, shortness of breath, uneven heartbeats, seizure).

Less serious side-effects may include:

  • Pain, numbness, or tingling where the implant was inserted
  • Minor bleeding or scarring where the implant was inserted
  • Menstrual cramps, changes in your menstrual periods
  • Mild headaches, dizziness, mood changes
  • Vaginal itching or discharge
  • Breast pain
  • Acne
  • Problems with contact lenses
  • Nausea, mild stomach pain
  • Back pain
  • Feeling nervous or depressed
  • Sore throat, flu symptoms
  • Weight gain 

Read more at http://www.drugs.com/mtm/nexplanon-implant.html#zUoFew4Ah26PcTL.99


Her reply on 1-3: “They are usually on my neck, shoulders, or stomach, but overall, I feel good, even if a little itchy.  Better than when I used the pill.”


RAH’s reply on 1-3: Which pill were you on?


To learn more about the advantages and disadvantages of the Nexplanon implant, go to our website: www.managingcontraception.com and click on Choices.  You can also order this wonderful new educational book from our website or by calling 404-875-5001.  Do you have your copy yet?

Key Words:  bites, hives, bedbugs, Nexplanon implant, side-effects, allergic reactions, etonorgestrel, contraceptive, breathing difficulty, swelling, lips, tongue, throat, numbness, weakness, severe pain, cramping, pelvic, headache, confusion, vision, cough, sneezing, blood, chest pain, breast lump, jaundice, depression, menstrual cramps, period, discharge, acne, nausea, contact lenses, sore throat, flu symptoms, weight pain

Robert A. Hatcher MD, MPH
Emeritus Professor of Gynecology and Obstetrics
Emory University School of Medicine
Atlanta, GA

The directors and owners of this website and any publications and information concerning health matters offered here advise a person with a particular problem to consult a primary-care clinician or a specialist in obstetrics, gynecology, or urology (depending on the problem or the contraceptive) as well as the product package insert and other references before diagnosing, managing, or treating the problem.
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